infective endocarditis after renal transplantation

background: infective endocarditis (ie) is a serious complication in immunosuppressive patients that has adverse effects. objectives: the aim of this study was to define the characteristics, outcomes, and correlating factors of mortality in renal transplant recipients. patients and methods: infective endocarditis was diagnosed in 22 patients from three renal transplant centers in iran between 2000 and 2010. modified duke criteria were applied to confirm the diagnosis. results: twenty-two renal transplant patients with ie were evaluated. blood culture results were positive in 81%. enteroccous and group d non-enterococcal were the causative microorganisms in 31% and 25% of patients, respectively. in-hospital and 12-month mortality was 41% and the mortality rate was higher in older patients in comparison to younger patients. overall, the rates of one-year disease-free patient and graft survival were 49% and 88%, respectively. conclusions: despite the availability of different and potent antibiotics, the mortality caused by ie remains considerably high. these patients are significantly prone to endovascular infections that affect the mortality and survival.